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I don't know if I understood your question correctly. To my knowledge, it is possible to use a Kinect and (one or more) additional device such as mouse, keyboard etc. on the same USB host; at least I've never heard otherwise. If a Kinect is the only connected device, though, you can be sure that no other device can interfere in any way. Which is probably why many people use it this way.

However, it is not possible to use more than one Kinect at the same USB host due to the required bandwidth (even when lowering the resolution as the bandwidth is negotiated when the device is plugged in). For technical details, see also this answer.