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I actually recently did this transition myself for my home machines.

If you attempt to go through the Ubuntu upgrade system to change to 18.04, you'll get about 80% done and it'll complain about some really esoteric things that couldn't be changed. I don't remember off hand. After a few hours of investigating, I figured it may be ROS because that's the only non-vanilla thing I have on my machine.

After uninstalling ROS, and attempting again, it worked fine. So yes, I would recommend fully uninstalling ROS Kinetic. After the upgrade, go through a fresh Melodic install.